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Articles (54)
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Inhibitory Effect of Apple Pectin and Culture Condensate of Bifidobacterium longum on Colorectal Tumors Induced by 1,2-Dimethylhydrazine in Transgenic Mice Harboring Human Prototype c-Ha-ras Genes.

OHNO, Kazuko, NARUSHIMA, Seiko, TAKEUCHI, Satomi, ITOH, Kikuji, MITSUOKA, Tomotari, NAKAYAMA, Hiroyuki, ITOH, Toshio, HIOKI, Kyoji, NOMURA, Tatsuji

Journal:

Experimental Animals

Année:

2000

Langue:

english

Fichier:

PDF, 15 KB

english, 2000

Development of an ex vivo cellular model of rheumatoid arthritis: Critical role of cd14-positive monocyte/macrophages in the development of pannus tissue

Toshiko Nozaki, Kyoko Takahashi, Osamu Ishii, Sachio Endo, Kyoji Hioki, Toshihito Mori, Tadahiro Kikukawa, Dimitrios T. Boumpas, Shoichi Ozaki, Hidehiro Yamada

Journal:

Arthritis & Rheumatism

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

Correlation of T cell receptor gene rearrangements to T cell surface antigen expression and to serum immunoglobulin level in scid mice

Sonoko Habu, Minoru Kimura, Motoya Katsuki, Kyoji Hioki, Tatsuji Nomura

Journal:

European Journal of Immunology

Année:

1987

Langue:

english

Fichier:

PDF, 535 KB

english, 1987

Abnormalities in cloned mice are not transmitted to the progeny

Nobuhiro Shimozawa, Yukiko Ono, Shingo Kimoto, Kyoji Hioki, Yoshihiko Araki, Yoichi Shinkai, Tomohiro Kono, Mamoru Ito

Journal:

genesis

Année:

2002

Langue:

english

Fichier:

PDF, 543 KB

english, 2002

Transgene stability and features of rasH2 mice as an animal model for short-term carcinogenicity testing

Hiroshi Suemizu, Kaori Muguruma, Chika Maruyama, Masashi Tomisawa, Minoru Kimura, Kyoji Hioki, Nobuhiro Shimozawa, Yasuyuki Ohnishi, Norikazu Tamaoki, Tatsuji Nomura

Journal:

Molecular Carcinogenesis

Année:

2002

Langue:

english

Fichier:

PDF, 195 KB

english, 2002

Diesel exhaust-induced airway hyperresponsiveness in c-Ha-ras transgenic mice

Jun-ichi Birumachi, Akira K. Suzuki, Kikuji Itoh, Kyoji Hioki, Chika Maruyama, Yasuyuki Ohnishi

Journal:

Toxicology

Année:

2001

Langue:

english

Fichier:

PDF, 139 KB

english, 2001

A kampo formula Juzen-taiho-to induces expression of metallothioneins in mice

Naoko Anjiki, Ritsuko Hoshino, Yasuyuki Ohnishi, Kyoji Hioki, Yoshifumi Irie, Atsushi Ishige, Kenji Watanabe

Journal:

Phytotherapy Research

Année:

2005

Langue:

english

Fichier:

PDF, 89 KB

english, 2005

Butylhydroxytoluene (BHT) increases susceptibility of transgenic rasH2 mice to lung carcinogenesis

Takashi Umemura, Yukio Kodama, Kyoji Hioki, Tohru Inoue, Tatsuji Nomura, Yuji Kurokawa

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

2001

Langue:

english

Fichier:

PDF, 257 KB

english, 2001

The Mouse rasH2/BHT Model as an in vivo Rapid Assay for Lung Carcinogens

Takashi Umemura, Yukio Kodama, Kyoji Hioki, Tatsuji Nomura, Akiyoshi Nishikawa, Masao Hirose, Yuji Kurokawa

Journal:

Cancer Science

Année:

2002

Langue:

english

Fichier:

PDF, 73 KB

english, 2002

Effects of cryopreservation of mouse embryos and in vitro fertilization on genotypic frequencies in colonies

Kazuo Goto, Kaori Muguruma, Takashi Kuramochi, Nobuhiro Shimozawa, Kyoji Hioki, Toshio Itoh, Michi Ebukuro

Journal:

Molecular Reproduction and Development

Année:

2002

Langue:

english

Fichier:

PDF, 73 KB

english, 2002

Developmental and Functional Analyses of CD8+ NK1.1+ T Cells in Class-I-Restricted TCR Transgenic Mice

Ryuichiro Ohwatari, Kazuya Iwabuchi, Chikako Iwabuchi, Taiki Morohashi, Hirofumi Sawa, Kyoji Hioki, Kimio Kobayashi, Satoshi Fukuda, Yukio Inuyama, Kazunori Onoé

Journal:

Cellular Immunology

Année:

2001

Langue:

english

Fichier:

PDF, 183 KB

english, 2001

The role of leptin in the development of the cortical neuron in mouse embryos

Jun Udagawa, Ryuju Hashimoto, Kyoji Hioki, Hiroki Otani

Journal:

Brain Research

Année:

2006

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2006

Role of x-linked immunodeficiency (xid) and NK activity in rejection of human tumor xenotransplants in nude mice

KOHJI MARUO, KAZUO SHIMAMURA, KYOJI HIOKI, MAMORU ITOH, YOSHITO UEYAMA, NORIKAZU TAMAOKI

Journal:

APMIS

Année:

1993

Langue:

english

Fichier:

PDF, 679 KB

english, 1993

Importance of the interferon-α system in murine large intestine indicated by microarray analysis of commensal bacteria-induced immunological changes

Kaori Munakata, Masahiro Yamamoto, Naoko Anjiki, Mitsue Nishiyama, Sachiko Imamura, Seiichi Iizuka, Kiyoe Takashima, Atsushi Ishige, Kyoji Hioki, Yasuyuki Ohnishi, Kenji Watanabe

Journal:

BMC Genomics

Année:

2008

Langue:

english

Fichier:

PDF, 816 KB

english, 2008

Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model

Takashi Umemura, Yukio Kodama, Akiyoshi Nishikawa, Kyoji Hioki, Tatsuji Nomura, Keita Kanki, Yuichi Kuroiwa, Yuji Ishii, Yuji Kurokawa, Masao Hirose

Journal:

Cancer Letters

Année:

2006

Langue:

english

Fichier:

PDF, 82 KB

english, 2006

The tyrosine kinase inhibitor imatinib [STI571] induces regression of xenografted canine mast cell tumors in SCID mice

Keiko Kobie, Mariko Kawabata, Kyoji Hioki, Akane Tanaka, Hiroshi Matsuda, Takashi Mori, Kohji Maruo

Journal:

Research in Veterinary Science

Année:

2007

Langue:

english

Fichier:

PDF, 107 KB

english, 2007

Susceptibility to urethane carcinogenesis of transgenic mice carrying a human prototype c-Ha-ras gene (rasH2 mice) and its modification by butylhydroxytoluene

Takashi Umemura, Yukio Kodama, Kyoji Hioki, Tohru Inoue, Tatsuji Nomura, Yuji Kurokawa

Journal:

Cancer Letters

Année:

1999

Langue:

english

Fichier:

PDF, 106 KB

english, 1999

Prostaglandin E2 Signaling and Bacterial Infection Recruit Tumor-Promoting Macrophages to Mouse Gastric Tumors

Hiroko Oshima, Kyoji Hioki, Boryana K. Popivanova, Keisuke Oguma, Nico Van Rooijen, Tomo–O. Ishikawa, Masanobu Oshima

Journal:

Gastroenterology

Année:

2011

Langue:

english

Fichier:

PDF, 6.44 MB

english, 2011

Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade

Kaori Munakata, Kiyoe Takashima, Mitsue Nishiyama, Naoko Asano, Akihito Mase, Kyoji Hioki, Yasuyuki Ohnishi, Masahiro Yamamoto, Kenji Watanabe

Journal:

BMC Genomics

Année:

2012

Langue:

english

Fichier:

PDF, 771 KB

english, 2012

A microarray analysis of gnotobiotic mice indicating that microbial exposure during the neonatal period plays an essential role in immune system development

Yamamoto, Masahiro, Yamaguchi, Rui, Munakata, Kaori, Takashima, Kiyoe, Nishiyama, Mitsue, Hioki, Kyoji, Ohnishi, Yasuyuki, Nagasaki, Masao, Imoto, Seiya, Miyano, Satoru, Ishige, Atsushi, Watanabe, Ken

Journal:

BMC Genomics

Année:

2012

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2012

A study on cryoprotectant solution suitable for vitrification of rat two-cell stage embryos

Eto, Tomoo, Takahashi, Riichi, Kamisako, Tsutomu, Hioki, Kyoji, Sotomaru, Yusuke

Journal:

Cryobiology

Année:

2014

Langue:

english

Fichier:

PDF, 304 KB

english, 2014

The Role of Leptin in the Development of the Cerebral Cortex in Mouse Embryos

Udagawa, Jun, Hashimoto, Ryuju, Suzuki, Hiroaki, Hatta, Toshihisa, Sotomaru, Yusuke, Hioki, Kyoji, Kagohashi, Yukiko, Nomura, Tatsuji, Minami, Yasuhiro, Otani, Hiroki

Journal:

Endocrinology

Année:

2006

Langue:

english

Fichier:

PDF, 868 KB

english, 2006

Effect of leptin administration on myelination in ob/ob mouse cerebrum after birth

Hashimoto, Ryuju, Matsumoto, Akihiro, Udagawa, Jun, Hioki, Kyoji, Otani, Hiroki

Journal:

Neuroreport

Année:

2013

Langue:

english

Fichier:

PDF, 714 KB

english, 2013

Characteristics of Multiple Primary Malignancies Associated with Lung Cancer by Gender

Haraguchi, Shuji, Hioki, Masafumi, Koizumi, Kiyoshi, Hisayoshi, Takao, Hirata, Tomomi, Akiyama, Hirohiko, Hirai, Kyoji, Mikami, Iwao, Kubokura, Hirotoshi, Shimizu, Kazuo

Journal:

Respiration

Année:

2007

Langue:

english

Fichier:

PDF, 78 KB

english, 2007

Supplement 1 || Validation of Transgenic Mice Carrying the Human Prototype c-Ha-ras Gene as a Bioassay Model for Rapid Carcinogenicity Testing

Satoshi Yamamoto, Koji Urano, Haruko Koizumi, Shigeharu Wakana, Kyoji Hioki, Kunitoshi Mitsumori, Yuji Kurokawa, Yuzo Hayashi and Tatsuji Nomura

Journal:

Environmental Health Perspectives

Année:

1998

Langue:

english

Fichier:

PDF, 591 KB

english, 1998

NFS/N-nu/+ Mice Can Macroscopically Be Distinguished from NFS/N-+/+ Littermates by Their Thymic Size and Shape

Kojima, Akinori, Saito, Muneo, Hioki, Kyoji, Shimanura, Kazuo, Habu, Sonoko

Journal:

Pathobiology

Année:

1984

Fichier:

PDF, 518 KB

1984

Inactivated Poliovirus Vaccine Protects Transgenic Poliovirus Receptor Mice against Type 3 Poliovirus Challenge

Rolf E. Taffs, Yelena V. Chernokhvostova, Eugenia M. Dragunsky, Tatsuji Nomura, Kyoji Hioki, E. Coen Beuvery, Edward A. Fitzgerald, Inessa S. Levenbook and David M. Asher

Journal:

The Journal of Infectious Diseases

Année:

1997

Langue:

english

Fichier:

PDF, 881 KB

english, 1997

Transfusion with Xenogeneic Erythrocytes into SCID Mice and Their Clearance from the Circulation.

ISHIHARA, Chiaki, TSUJI, Masayoshi, HAGIWARA, Katsuro, HIOKI, Kyoji, ARIKAWA, Jiro, AZUMA, Ichiro

Journal:

Journal of Veterinary Medical Science

Année:

1994

Fichier:

PDF, 912 KB

1994

Erythrocyte-Replaced Mouse Model for Haemoparasite Studies: Comparison of NOD/shi-scid and C.B-17/Jcl-scid Mouse upon Acceptability of Human Erythrocytes

ISHIHARA, Chiaki, ZAMOTO, Aya, TSUJI, Masayoshi, WEI, Qiang, AZUMA, Ichiro, HIOKI, Kyoji

Journal:

Journal of Veterinary Medical Science

Année:

2003

Langue:

english

Fichier:

PDF, 192 KB

english, 2003

Pneumocystis carinii Cysts are Susceptible to Inactivation by Chemical Disinfectants.

KURAMOCHI, Takashi, HIOKI, Kyoji, ITO, Mamoru

Journal:

Experimental Animals

Année:

1997

Fichier:

PDF, 393 KB

1997

Phenotypes of IRS-2 Deficient Mice Produced by Reproductive Technology are Stable

HASHIMOTO, Haruo, ARAI, Toshiro, OHNISHI, Yasuyuki, ETO, Tomoo, ITO, Mamoru, HIOKI, Kyoji, SUZUKI, Ryo, YAMAUCHI, Toshimasa, OHSUGI, Mitsuru, SAITO, Muneo, UEYAMA, Yoshito, TOBE, Kazuyuki, KADOWAKI, T

Journal:

Experimental Animals

Année:

2007

Langue:

english

Fichier:

PDF, 222 KB

english, 2007

An Efficient Reproductive Method for Irs2-/- Mice with C57BL/6JJcl Genetic Background

HASHIMOTO, Haruo, ETO, Tomoo, KAMISAKO, Tsutomu, HOYA, Naoko, HATAKEYAMA, Teruhiko, ARAI, Toshiro, YOKOSUKA, Makoto, OHNISHI, Yasuyuki, ITO, Mamoru, HIOKI, Kyoji, SUZUKI, Ryo, OHSUGI, Mitsuru, SAITO,

Journal:

Experimental Animals

Année:

2008

Langue:

english

Fichier:

PDF, 763 KB

english, 2008

Experimental Chemotherapy against Canine Mammary Cancer Xenograft in SCID Mice and Its Prediction of Clinical Effect.

YAMASHITA, Atsuko, MARUO, Kohji, SUZUKI, Kaoru, SHIROTA, Kinji, KOBAYASHI, Kimio, HIOKI, Kyoji

Journal:

Journal of Veterinary Medical Science

Année:

2001

Langue:

english

Fichier:

PDF, 92 KB

english, 2001

Chemotherapeutic Profiles of Human Tumors Implanted in SCID Mice Showing Appreciable Inconsistencies with Those in Nude Mice.

YOSHIMURA, Masumi, ENDO, Sachio, HIOKI, Kyoji, UEYAMA, Yoshito, OHNISHI, Yasuyuki

Journal:

Experimental Animals

Année:

1997

Fichier:

PDF, 217 KB

1997

PCR Method for Genotyping and Zygosity-Testing of RasH2 Transgenic Mice

SUEMIZU, Hiroshi, KITO-MARUYAMA, Chika, SOTOMARU, Yusuke, OGURA, Tomoyuki, HIOKI, Kyoji, OHNISHI, Yasuyuki, TAMAOKI, Norikazu

Journal:

Experimental Animals

Année:

2004

Langue:

english

Fichier:

PDF, 94 KB

english, 2004

Sedative Effect of Medetomidine and its Reversal by Atipamezole in House Musk Shrews (Suncus murinus).

TAGAWA, Masahiro, HARA, Yasushi, EJIMA, Hiroyasu, KOMORI, Shinobu, SAITO, Toru R., TAKAHASHI, Kazuaki W., HIOKI, Kyoji, EBUKURO, Susumu

Journal:

Experimental Animals

Année:

1995

Fichier:

PDF, 392 KB

1995

Sleep-Time Variation for Ethanol and the Hypnotic Drugs Tribromoethanol, Urethane, Pentobarbital, and Propofol within Outbred ICR Mice.

KOIZUMI, Tsutomu, MAEDA, Hideyuki, HIOKI, Kyoji

Journal:

Experimental Animals

Année:

2002

Fichier:

PDF, 934 KB

2002

Effect of Mouse Intestinal Bacteria on Incidence of Colorectal Tumors Induced by 1,2-dimethylhydrazine Injection in Gnotobiotic Transgenic Mice Harboring Human Prototype c-Ha-ras Genes.

NARUSHIMA, Seiko, ITOH, Kikuji, MITSUOKA, Tomotari, NAKAYAMA, Hiroyuki, ITOH, Toshio, HIOKI, Kyoji, NOMURA, Tatsuji

Journal:

Experimental Animals

Année:

1998

Fichier:

PDF, 988 KB

1998

Lack of B Cell Leakiness in BALB/cA-nu, scid Double Mutant Mice.

HIOKI, Kyoji, KURAMOCHI, Takashi, ENDOH, Sachio, TERADA, Ehji, UEYAMA, Yoshito, ITO, Mamoru

Journal:

Experimental Animals

Année:

2001

Langue:

english

Fichier:

PDF, 49 KB

english, 2001

Direct Production of Gene-targeted Mice from ES Cells by Nuclear Transfer and Gene Transmission to their Progeny.

SHIMOZAWA, Nobuhiro, ONO, Yukiko, MUGURUMA, Kaori, HIOKI, Kyoji, ARAKI, Yoshihiko, SHINKAI, Yoichi, KONO, Tomohiro, ITO, Mamoru

Journal:

Experimental Animals

Année:

2002

Fichier:

PDF, 569 KB

2002

A Genetic Quality Testing System for Early Stage Embryos in the Mouse

KATOH, Hideki, ODA, Koji, HIOKI, Kyoji, MUGURUMA, Kaori

Journal:

Experimental Animals

Année:

2003

Langue:

english

Fichier:

PDF, 27 KB

english, 2003

Estrous Stage- and Animal Age-Independent Superovulation in the BrlHan:WIST@Jcl(GALAS) Rat

SOTOMARU, Yusuke, KAMISAKO, Tsutomu, HIOKI, Kyoji

Journal:

Experimental Animals

Année:

2005

Langue:

english

Fichier:

PDF, 81 KB

english, 2005

Inhibitory Effect of Yogurt on Aberrant Crypt Foci Formation in the Rat Colon and Colorectal Tumorigenesis in RasH2 Mice

NARUSHIMA, Seiko, SAKATA, Tadashi, HIOKI, Kyoji, ITOH, Toshio, NOMURA, Tatsuji, ITOH, Kikuji

Journal:

Experimental Animals

Année:

2010

Langue:

english

Fichier:

PDF, 446 KB

english, 2010

Establishment of a Highly Reproducible Model of Human/Murine SCID Mouse Arthritis.

ISHII, Osamu, YAMADA, Hidehiro, KIKUKAWA, Tadahiro, ENDHO, Sachio, HIOKI, Kyoji, ABE, Chiyuki, ICHIKAWA, Yoichi

Journal:

Proceedings of The Japanese Society of Animal Models for Human Diseases

Année:

1997

Langue:

english

Fichier:

PDF, 326 KB

english, 1997

Histological Study of the Hypertrophic Placentas and Open Eyelids Observed in Cloned Fetuses

SHIMOZAWA, Nobuhiro, TAJIMA, Shingo, AZUMA, Noriyuki, HIOKI, Kyoji, KONO, Tomohiro, ITO, Mamoru

Journal:

Journal of Reproduction and Development

Année:

2003

Fichier:

PDF, 230 KB

2003

A New Mouse Model of Genetically Transmitted Polycystic Kidney Disease

Takahashi, Hisahide, Ueyama, Yoshito, Hibino, Tsutomu, Kuwahara, Yuko, Suzuki, Shuzo, Hioki, Kyoji, Tamaoki, Norikazu

Journal:

The Journal of Urology

Année:

1986

Langue:

english

Fichier:

PDF, 316 KB

english, 1986

Absence of T Lymphocyte Functions in Athymic Nude Rats

TERADA, Eiji, NAKAYAMA, Taro, HIOKI, Kyoji, SAITO, Muneo, OKUDAIRA, Hirokazu

Journal:

Experimental Animals

Année:

1980

Langue:

english

Fichier:

PDF, 258 KB

english, 1980

Diurnal Rhythms in Locomotor Activity of the House Musk Shrew, Suncus murinus

AOKI, Shinobu, SAITO, Toru R., EBUKURO, Susumu, HIOKI, Kyoji, TAKAHASHI, Kazuaki W.

Journal:

Experimental Animals

Année:

1993

Langue:

english

Fichier:

PDF, 305 KB

english, 1993

Elimination of Mouse Hepatitis Virus Infection in Human Malignant Tumors Transplanted into Athymic (Nude) Mice

MARUO, Kohji, ENDO, Yukio, ITO, Toshio, TAKAKURA, Akira, HIOKI, Kyoji, IWAI, Hiroshi

Journal:

Experimental Animals

Année:

1982

Fichier:

PDF, 395 KB

1982

A Metabolomic-Based Evaluation of the Role of Commensal Microbiota throughout the Gastrointestinal Tract in Mice

Yamamoto, Yuri, Nakanishi, Yumiko, Murakami, Shinnosuke, Aw, Wanping, Tsukimi, Tomoya, Nozu, Ryoko, Ueno, Masami, Hioki, Kyoji, Nakahigashi, Kenji, Hirayama, Akiyoshi, Sugimoto, Masahiro, Soga, Tomoyo

Journal:

Microorganisms

Année:

2018

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2018